Photo of Douglas Lester

Douglas Lester

Lecturer

  • 807 Citations
  • 17 h-Index
1989 …2018
If you made any changes in Pure these will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Retinitis Pigmentosa Medicine & Life Sciences
Retinal Degeneration Medicine & Life Sciences
Chondrocytes Medicine & Life Sciences
Chickens Medicine & Life Sciences
Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Growth Plate Medicine & Life Sciences
Rhodopsin Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1989 2018

Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity

Brown, S. G., Miller, M. R., Lishko, P. V., Lester, D. H., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S., 1 Oct 2018, In : Human Reproduction. 33, 10, p. 1812-1816 5 p.

Research output: Contribution to journalArticle

Open Access
File
Spermatozoa
Cations
Exons
Exome
Mutation

Correction to the pathogenic alternative splicing, caused by the common GNB3 c.825C>T allele, using a novel, antisense morpholino

McGlinchey, J. C. P., Tummala, H. & Lester, D. H., 1 Aug 2016, In : Nucleic Acid Therapeutics. 26, 4, p. 257-265 9 p.

Research output: Contribution to journalArticle

Open Access
File
Morpholinos
Alternative Splicing
Alleles
Exons
RNA Splice Sites

Exome sequencing and subsequent haplotype analysis of a Scottish Cone-Rod patient, homozygous for a common “Spanish” CERKL mutation, points towards a distant common ancestry

Cassidy, A. J., Brugnatelli, S. V., Ayuso, C., Avila-Fernandez, A., Zeller, D., Lester, D. H. & The Tayside Centre For Genomic Analysis, 2016, p. 1398 1 p.

Research output: Contribution to conferencePoster

Open Access

Correction of the pathogenic alternative splicing, caused by the common GNB3 c.825C > T allele, using a novel, antisense morpholino

McGlinchey, J. C. P. & Lester, D. H., 10 Sep 2015, In : Human Gene Therapy. 26, 9, p. A20-A21 2 p.

Research output: Contribution to journalMeeting Abstract

Open Access

Antisense oligonucleotides or oligonucleotide analogues

Lester, D. H., 20 Nov 2013, IPC No. C12N 15/00; A61K 31/00; A61P 43/00, Irish Patents Office, Patent No. S86306, Priority date 26 Mar 2013, Priority No. S2013/0118

Research output: Patent

File
Antisense Oligonucleotides
Patents and inventions
Oligonucleotides
Morpholinos
RNA Precursors

Thesis

A phylogenetic study of Ubiquitin Conjugating Enzymes and structural analysis of human UBE2J proteins

Author: Mukherjee, J., Oct 2006

Supervisor: Lester, D. H. (Supervisor)

Student thesis: Doctoral Thesis

File

Genes and protein structural elements are delineated by DNA mirror repeats and characterized by net dinucleotide composition

Author: Lang, D., May 2009

Supervisor: Palfreyman, J. W. (Supervisor) & Lester, D. H. (Supervisor)

Student thesis: Doctoral Thesis

File