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James Bown

Professor of Systems Biology

  • 371 Citations
  • 11 h-Index
19982018
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Research Output 1998 2018

Identifying prognostic structural features in tissue sections of colon cancer patients using point pattern analysis

Jones-Todd, C. M., Caie, P., Illian, J. B., Stevenson, B. C., Savage, A., Harrison, D. J. & Bown, J. L., 28 Nov 2018, In : Statistics in Medicine.

Research output: Contribution to journalArticle

Colorectal Cancer
Pattern Analysis
Point Process
Colonic Neoplasms
Cancer

Narratives for drug design

Bown, J. L. & Goltsov, A., 24 Nov 2018, Narrating complexity. Walsh, R. & Stepney, S. (eds.). Springer, p. 253-268 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug Design
Neoplasms
Decision Making
Pharmaceutical Preparations

Unsupervised machine learning of integrated health and social care data from the Macmillan Improving the Cancer Journey service in Glasgow

Kang, K. L., Greer, M., Bown, J. L., Preston, J., Mabelis, J., Hepburn, L-A., Fisher, M., Falconer, R. E., McDermott, S. & Deed, S., 1 Nov 2018, In : British Journal of Cancer. 119, 1 p., 4.

Research output: Contribution to journalMeeting Abstract

Open Access
File
Delivery of Health Care
Neoplasms
Aptitude
Needs Assessment
Resource Allocation

A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT

Bown, J. L., Shovman, M., Robertson, P., Boiko, A., Goltsov, A., Mullen, P. & Harrison, D. J., 2017, In : Oncotarget. 8, p. 29657-29667 11 p.

Research output: Contribution to journalArticle

Open Access
File
Biomarkers
Systems Biology
Therapeutics
Video Games
Drug Resistance
1 Citations

Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002

Goltsov, A., Tashkandi, G., Langdon, S. P., Harrison, D. J. & Bown, J. L., 15 Jan 2017, In : European Journal of Pharmaceutical Sciences. 97, p. 170–181 12 p.

Research output: Contribution to journalArticle

Open Access
File
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Sirolimus
Phosphoric Monoester Hydrolases
Phosphotransferases
Enzymes

Thesis

Agent-based modelling of cell-cell interactions for in vitro vascular formation and cancer cell growth

Author: Li, Y., Nov 2015

Supervisor: Bown, J. L. (Supervisor)

Student thesis: Doctoral Thesis

File

Data-driven modelling and optimised reverse engineering of complex dynamical systems in cancer research

Author: Idowu, M. A., Jul 2013

Supervisor: Bown, J. L. (Supervisor)

Student thesis: Doctoral Thesis

File

Meme transmission in artificial proto-cultures

Author: Guest, A., Aug 2013

Supervisor: Bown, J. L. (Supervisor)

Student thesis: Doctoral Thesis

File