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Sean Brown

Senior Lecturer

  • 150 Citations
  • 8 h-Index
20052018
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  • 1 Similar Profiles
Spermatozoa Medicine & Life Sciences
Progesterone Medicine & Life Sciences
Fertilization Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Intracytoplasmic Sperm Injections Medicine & Life Sciences
Cations Medicine & Life Sciences
Phospholipids Medicine & Life Sciences
Sperm Motility Medicine & Life Sciences

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Research Output 2005 2018

  • 150 Citations
  • 8 h-Index
  • 14 Article

Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity

Brown, S. G., Miller, M. R., Lishko, P. V., Lester, D. H., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S., 1 Oct 2018, In : Human Reproduction. 33, 10, p. 1812-1816 5 p.

Research output: Contribution to journalArticle

Spermatozoa
Cations
Exons
Exome
Mutation
1 Citations

Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome

Kelly, M. C., Brown, S. G., Costello, S. M., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S., 1 Jun 2018, In : Human Reproduction. 33, 6, p. 1023-1033 11 p., dey096.

Research output: Contribution to journalArticle

Open Access
File
Single-Cell Analysis
Fertilization
Progesterone
Intracytoplasmic Sperm Injections
Tissue Donors
3 Citations

Complex CatSper-dependent and independent [Ca2+]i signalling in human spermatozoa induced by follicular fluid

Brown, S. G., Costello, S., Kelly, M. C., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S., 1 Oct 2017, In : Human Reproduction. 32, 10, p. 1995-2006 12 p.

Research output: Contribution to journalArticle

Open Access
File
Follicular Fluid
Spermatozoa
Progesterone
Tissue Donors
Research Ethics
2 Citations

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem

Martins da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., 1 May 2017, In : Human Reproduction. 32, 5, p. 974-984 11 p.

Research output: Contribution to journalArticle

Open Access
File
Male Infertility
Drug Discovery
Spermatozoa
Sperm-Ovum Interactions
Sperm Motility
14 Citations

Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF

Brown, S. G., Publicover, S. J., Mansell, S. A., Lishko, P. V., Williams, H. L., Ramalingam, M., Wilson, S. M., Barratt, C. L. R., Sutton, K. A. & Martins da Silva, S. J., 6 Apr 2016, In : Human Reproduction. 31, 6, p. 1147-1157 11 p.

Research output: Contribution to journalArticle

Open Access
File
Fertilization
Membrane Potentials
Infertility
Spermatozoa
Intracytoplasmic Sperm Injections

Thesis

Role of second generation phosphodiesterase inhibitors on mammalian sperm mobility

Author: Madamidola, O., 2015

Supervisor: Brown, S. G. (Supervisor) & Adya, A. K. (Supervisor)

Student thesis: Doctoral Thesis

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