• 212 Citations
  • 9 h-Index
20052019

Research output per year

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Personal profile

Personal profile

My research interests are focused on reproductive physiology – in particular, the regulation of sperm function. In collaboration with Professor Chris Barratt at the University of Dundee and NHS Tayside, I’m investigating ion channel (dys)function in human sperm. From a research perspective, I’m also interested in pedagogic research in online teaching.

I completed my PhD in Neuroscience at University College London.  Before joining Abertay University as a lecturer, I held postdoctoral research positions at University College London and the University of Dundee. My research experience includes investigating the electrophysiological and molecular analysis of GIRK channels, and the intracellular signalling pathways controlling ENaC expression.

I have previously acted as an external examiner for the Biotechnology degree at the Modern Science and Arts University in Cairo, Egypt.

Teaching

Undergraduate module leader responsibilities;

  • LSC102 - Human Physiology
  • LSC204 - Medical Physiology
  • LSC303 - Transfusion Science
  • LSC404 - Advanced Pathophysiology

Dr. Brown has a pedagogic research interest in the area of online teaching/learning and assessment.

Research interests

Dr. Brown is currently working in collaboration with Professor Chris Barratt at the University of Dundee and NHS Tayside working on the pathophysiology of human sperm.  His background is as an electrophysiologist (patch clamp) and has an interest in the molecular control of ion channel function and is currently involved in a studying examining ion channel (dys)function in human sperm.

Funding

Dr. Brown has been the recipient of Tenovus Scotland, Carnegie Scotland, Medical Research Council and Chief Scientist office grants.

Esteem

External examiner for Biotechnology degree at  Modern Science and Arts University, Cairo, Egypt (2012-14).

Reviewer for Human reproduction

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Research Output

  • 212 Citations
  • 9 h-Index
  • 16 Article
  • 1 Abstract

Human sperm ion channel (dys)function: implications for fertilization

Brown, S. G., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S. J., 5 Nov 2019, In : Human Reproduction Update. 25, 6, p. 758-776 19 p., dmz032.

Research output: Contribution to journalArticle

Open Access
File
  • 2 Citations (Scopus)
    48 Downloads (Pure)

    Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function

    McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., 26 Dec 2019, In : British Journal of Pharmacology. 176, 23, p. 4521-4536 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 61 Downloads (Pure)

    The intracellular actions of trequinsin hydrochloride promotes human sperm motility

    McBrinn, R., Brown, S. G., Fraser, J., Barratt, C. L. R., Martins da Silva, S., Gray, D. W. & Hope, A. G., 5 Jan 2019.

    Research output: Contribution to conferenceAbstract

  • Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity

    Brown, S. G., Miller, M. R., Lishko, P. V., Lester, D. H., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S., 1 Oct 2018, In : Human Reproduction. 33, 10, p. 1812-1816 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 10 Citations (Scopus)
    50 Downloads (Pure)

    Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome

    Kelly, M. C., Brown, S. G., Costello, S. M., Ramalingam, M., Drew, E., Publicover, S. J., Barratt, C. L. R. & Martins da Silva, S., 1 Jun 2018, In : Human Reproduction. 33, 6, p. 1023-1033 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 6 Citations (Scopus)
    75 Downloads (Pure)