Psychomotor skills are a series of cognitive abilities often linked with physical movement, coordination and speed that individuals use, to progress through cognitive stages in order to demonstrate fine motor skills. This paper investigates whether or not playing a video game could potentially influence and improve the psychomotor skills of adolescents, particularly their eye-hand coordination, visual response and attention competence, the aim being to provide statistical evidence that video games can be potentially used to enhance psychomotor skills. A total of 62 participants were invited to participate in an experimental study where these participants were divided into two groups, the control group and the experimental group. The participants were aged between 16 and 19 years, and they were asked to complete a building block task that is closely associated with using psychomotor skills, and they did not have any prior experience of. A pre – post study design was used in both groups in order to measure participants’ level of confidence in using their psychomotor skills. Furthermore, the study investigated if the participants in the experimental group integrated elements of video game play into intentional and automatic real-life reactions within the building block task they undertook. The findings of the study suggest that those participants who played the video game were more confident in using their eye-hand coordination and visual response, and managed to complete the natural building block task faster and more accurately than the participants who did not play the video game.