An in situ amperometric biosensor for the detection of vapours from explosive compounds

Christopher David Gwenin, Maher Kalaji*, Catharine Melanie Kay, Peter Anthony Williams, Duarte Novaes Tito

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


An amperometric biosensor based on genetically-modified enzymes was used for the in situ detection of trace vapours from a number of explosive compounds. The vapour samples that were generated from a purpose-built vapour generator were collected and pre-concentrated using a trap able to concentrate samples at a rate of 60-fold per minute of sampling. The amperometric biosensor achieved a remarkably low vapour detection limit of 6 parts per trillion from a room temperature sample. The specific activity of the reported enzyme toward a number of explosive compounds was also confirmed using absorbance measurements.

Original languageEnglish
Pages (from-to)621-625
Number of pages5
Issue number5
Early online date30 Nov 2007
Publication statusPublished - May 2008
Externally publishedYes

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