Arabino mycolates from synthetic mycolic acids

Mohsin O. Mohammed, Mark S. Baird*, Juma'a R. Al Dulayymi, Alison Jones, Christopher D. Gwenin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.

Original languageEnglish
Pages (from-to)2849-2857
Number of pages9
JournalTetrahedron
Volume72
Issue number22
Early online date31 Mar 2016
DOIs
Publication statusPublished - 2 Jun 2016
Externally publishedYes

Keywords

  • Mycobacteria
  • Tuberculosis
  • Arabino mycolates
  • Antigens

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