Differential responses to antimycin A and expressions of the Crabtree effect in selected Kluyveromyces spp.

G. Liti, F. R. Wardrop, G. Cardinali, Alessandro Martini, Graeme M. Walker

Research output: Contribution to journalArticle

Abstract

When cells of selected Kluyveromyces strains were aerobically propagated in batch culture with glucose, cell growth, oxygen uptake and ethanol production exhibited differential responses to the respiratory inhibitor, antimycin A. Even within the species Kluyveromyces lactis (sensu Vaughan-Martini and Martini), which was previously thought to be genetically homogeneous, metabolic heterogeneity was observed among the type strains, representing the four formerly different species now grouped with the epithet K. lactis. Results of this study support the concept of physiological biodiversity within the species K. lactis, and suggest that expression of the Crabtree effect is more highly variable in these yeasts than previously thought.
Original languageEnglish
Pages (from-to)235-243
Number of pages9
JournalAnnals of Microbiology
Volume51
StatePublished - 2001

Fingerprint

Antimycin A
Kluyveromyces
Batch Cell Culture Techniques
Biodiversity
Ethanol
Yeasts
Oxygen
Glucose

Cite this

Liti, G.; Wardrop, F. R.; Cardinali, G.; Martini, Alessandro; Walker, Graeme M. / Differential responses to antimycin A and expressions of the Crabtree effect in selected Kluyveromyces spp.

In: Annals of Microbiology, Vol. 51, 2001, p. 235-243.

Research output: Contribution to journalArticle

@article{669c07a1de8149c5ba14f7f6a514ec4d,
title = "Differential responses to antimycin A and expressions of the Crabtree effect in selected Kluyveromyces spp.",
abstract = "When cells of selected Kluyveromyces strains were aerobically propagated in batch culture with glucose, cell growth, oxygen uptake and ethanol production exhibited differential responses to the respiratory inhibitor, antimycin A. Even within the species Kluyveromyces lactis (sensu Vaughan-Martini and Martini), which was previously thought to be genetically homogeneous, metabolic heterogeneity was observed among the type strains, representing the four formerly different species now grouped with the epithet K. lactis. Results of this study support the concept of physiological biodiversity within the species K. lactis, and suggest that expression of the Crabtree effect is more highly variable in these yeasts than previously thought.",
author = "G. Liti and Wardrop, {F. R.} and G. Cardinali and Alessandro Martini and Walker, {Graeme M.}",
year = "2001",
volume = "51",
pages = "235--243",
journal = "Annals of Microbiology",

}

Differential responses to antimycin A and expressions of the Crabtree effect in selected Kluyveromyces spp. / Liti, G.; Wardrop, F. R.; Cardinali, G.; Martini, Alessandro; Walker, Graeme M.

In: Annals of Microbiology, Vol. 51, 2001, p. 235-243.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Differential responses to antimycin A and expressions of the Crabtree effect in selected Kluyveromyces spp.

AU - Liti,G.

AU - Wardrop,F. R.

AU - Cardinali,G.

AU - Martini,Alessandro

AU - Walker,Graeme M.

PY - 2001

Y1 - 2001

N2 - When cells of selected Kluyveromyces strains were aerobically propagated in batch culture with glucose, cell growth, oxygen uptake and ethanol production exhibited differential responses to the respiratory inhibitor, antimycin A. Even within the species Kluyveromyces lactis (sensu Vaughan-Martini and Martini), which was previously thought to be genetically homogeneous, metabolic heterogeneity was observed among the type strains, representing the four formerly different species now grouped with the epithet K. lactis. Results of this study support the concept of physiological biodiversity within the species K. lactis, and suggest that expression of the Crabtree effect is more highly variable in these yeasts than previously thought.

AB - When cells of selected Kluyveromyces strains were aerobically propagated in batch culture with glucose, cell growth, oxygen uptake and ethanol production exhibited differential responses to the respiratory inhibitor, antimycin A. Even within the species Kluyveromyces lactis (sensu Vaughan-Martini and Martini), which was previously thought to be genetically homogeneous, metabolic heterogeneity was observed among the type strains, representing the four formerly different species now grouped with the epithet K. lactis. Results of this study support the concept of physiological biodiversity within the species K. lactis, and suggest that expression of the Crabtree effect is more highly variable in these yeasts than previously thought.

M3 - Article

VL - 51

SP - 235

EP - 243

JO - Annals of Microbiology

T2 - Annals of Microbiology

JF - Annals of Microbiology

ER -