Drug activation system

Christopher Gwenin (Inventor), Maher Kalaji (Inventor), Vanessa Roberts (Inventor)

Research output: Patent


The present invention discloses a drug activator carrier comprising: a) particles having a metallic or metallic oxide core prepared from a paramagnetic material, said metallic core being coated with a coating material selected from polymer, metal or metal oxide; b) a biological material, having reductase activity, bound onto the metal coating the particles of step a), and wherein said biological material is capable of activating non-toxic pro-drugs into active and toxic drugs suitable for treating a disease; said drug activator carrier allowing targeted delivery of the toxic drug.
Original languageEnglish
Patent numberWO 2011/026898 A2
IPCA61K 47/48,A61P 35/00
Priority date2/09/09
Filing date2/09/10
Publication statusPublished - 10 Mar 2011
Externally publishedYes


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