Abstract
The present invention discloses a drug activator carrier comprising: a) particles having a metallic or metallic oxide core prepared from a paramagnetic material, said metallic core being coated with a coating material selected from polymer, metal or metal oxide; b) a biological material, having reductase activity, bound onto the metal coating the particles of step a), and wherein said biological material is capable of activating non-toxic pro-drugs into active and toxic drugs suitable for treating a disease; said drug activator carrier allowing targeted delivery of the toxic drug.
| Original language | English |
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| Patent number | WO 2011/026898 A2 |
| IPC | A61K 47/48,A61P 35/00 |
| Priority date | 2/09/09 |
| Filing date | 2/09/10 |
| Publication status | Published - 10 Mar 2011 |
| Externally published | Yes |