Gene transfer in higher animals: theoretical considerations and key concepts

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Abstract

Gene transfer technology provides the ability to genetically manipulate the cells of higher animals. Gene transfer permits both germline and somatic alterations. Such genetic manipulation is the basis for animal transgenesis goals and gene therapy attempts. Improvements in gene transfer are required in terms of transgene design to permit gene targeting, and in terms of transfection approaches to allow improved transgene uptake efficiencies.
Original languageEnglish
Pages (from-to)1-22
Number of pages22
JournalJournal of Biotechnology
Volume99
Issue number1
DOIs
StatePublished - Oct 2002

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Genes
Transgenes
Technology Transfer
Gene Transfer Techniques
Gene Targeting
Genetic Therapy
Transfection

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Smith, Kevin R. / Gene transfer in higher animals : theoretical considerations and key concepts.

In: Journal of Biotechnology, Vol. 99, No. 1, 10.2002, p. 1-22.

Research output: Contribution to journalArticle

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Gene transfer in higher animals : theoretical considerations and key concepts. / Smith, Kevin R.

In: Journal of Biotechnology, Vol. 99, No. 1, 10.2002, p. 1-22.

Research output: Contribution to journalArticle

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