Polyphenol-rich dark chocolate in treatment of diabetes mellitus risk factors

Emad A. S. Al-Dujaili; Catherine Tsang; Suzana Almoosawi

doi:10.1007/978-1-61779-803-0_25

Polyphenol-rich dark chocolate in treatment of diabetes mellitus risk factors

Emad A. S. Al-Dujaili, Catherine Tsang, Suzana Almoosawi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

Type 2 diabetes is generally characterized by hyperglycemia, insulin resistance (reduced insulin sensitivity), and obesity, which is associated with not only diabetes but also hyperlipidemia and hypertension.
Evidence from the past 10 years demonstrates that moderate intake of dark chocolate may exert protective effects against the development of type 2 diabetes risk factors; however, large-scale clinical trials are required.
Several mechanisms have been proposed to explain the chocolate’s positive effects, not only on insulin sensitivity and vascular endothelial function but also its metabolic (fat and carbohydrate), antihypertensive, antithrombotic, and anti-inflammatory effects.
Polyphenol-rich chocolate may potentially be used as a nutraceutical medication to help treat diabetes, strokes, and vascular dementia; thus, future studies should provide information on polyphenol content and the flavanol plasma levels achieved.

Original language	English
Title of host publication	Chocolate in health and nutrition
Editors	Ronald R. Watson, Victor R. Preedy, Sherma Zibadi
Place of Publication	New York
Publisher	Humana Press
Pages	341-353
Number of pages	13
ISBN (Electronic)	9781617798030
ISBN (Print)	9781617798023
DOIs	https://doi.org/10.1007/978-1-61779-803-0_25
Publication status	Published - 2013

Publication series

Name	Nutrition and Health
Publisher	Humana Press
Volume	7

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10.1007/978-1-61779-803-0_25

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abstract = "Type 2 diabetes is generally characterized by hyperglycemia, insulin resistance (reduced insulin sensitivity), and obesity, which is associated with not only diabetes but also hyperlipidemia and hypertension.Evidence from the past 10 years demonstrates that moderate intake of dark chocolate may exert protective effects against the development of type 2 diabetes risk factors; however, large-scale clinical trials are required.Several mechanisms have been proposed to explain the chocolate{\textquoteright}s positive effects, not only on insulin sensitivity and vascular endothelial function but also its metabolic (fat and carbohydrate), antihypertensive, antithrombotic, and anti-inflammatory effects.Polyphenol-rich chocolate may potentially be used as a nutraceutical medication to help treat diabetes, strokes, and vascular dementia; thus, future studies should provide information on polyphenol content and the flavanol plasma levels achieved.",

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Polyphenol-rich dark chocolate in treatment of diabetes mellitus risk factors. / Al-Dujaili, Emad A. S.; Tsang, Catherine; Almoosawi, Suzana.

Chocolate in health and nutrition. ed. / Ronald R. Watson; Victor R. Preedy; Sherma Zibadi. New York : Humana Press, 2013. p. 341-353 (Nutrition and Health; Vol. 7).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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