Abstract
Evidence from the past 10 years demonstrates that moderate intake of dark chocolate may exert protective effects against the development of type 2 diabetes risk factors; however, large-scale clinical trials are required.
Several mechanisms have been proposed to explain the chocolate’s positive effects, not only on insulin sensitivity and vascular endothelial function but also its metabolic (fat and carbohydrate), antihypertensive, antithrombotic, and anti-inflammatory effects.
Polyphenol-rich chocolate may potentially be used as a nutraceutical medication to help treat diabetes, strokes, and vascular dementia; thus, future studies should provide information on polyphenol content and the flavanol plasma levels achieved.
| Original language | English |
|---|---|
| Title of host publication | Chocolate in health and nutrition |
| Editors | Ronald R. Watson, Victor R. Preedy, Sherma Zibadi |
| Place of Publication | New York |
| Publisher | Humana Press |
| Pages | 341-353 |
| Number of pages | 13 |
| ISBN (Electronic) | 9781617798030 |
| ISBN (Print) | 9781617798023 |
| DOIs | |
| Publication status | Published - 2013 |
Publication series
| Name | Nutrition and Health |
|---|---|
| Publisher | Humana Press |
| Volume | 7 |
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Polyphenol-rich dark chocolate in treatment of diabetes mellitus risk factors. / Al-Dujaili, Emad A. S.; Tsang, Catherine; Almoosawi, Suzana.
Chocolate in health and nutrition. ed. / Ronald R. Watson; Victor R. Preedy; Sherma Zibadi. New York : Humana Press, 2013. p. 341-353 (Nutrition and Health; Vol. 7).Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Polyphenol-rich dark chocolate in treatment of diabetes mellitus risk factors
AU - Al-Dujaili, Emad A. S.
AU - Tsang, Catherine
AU - Almoosawi, Suzana
PY - 2013
Y1 - 2013
N2 - Type 2 diabetes is generally characterized by hyperglycemia, insulin resistance (reduced insulin sensitivity), and obesity, which is associated with not only diabetes but also hyperlipidemia and hypertension.Evidence from the past 10 years demonstrates that moderate intake of dark chocolate may exert protective effects against the development of type 2 diabetes risk factors; however, large-scale clinical trials are required.Several mechanisms have been proposed to explain the chocolate’s positive effects, not only on insulin sensitivity and vascular endothelial function but also its metabolic (fat and carbohydrate), antihypertensive, antithrombotic, and anti-inflammatory effects.Polyphenol-rich chocolate may potentially be used as a nutraceutical medication to help treat diabetes, strokes, and vascular dementia; thus, future studies should provide information on polyphenol content and the flavanol plasma levels achieved.
AB - Type 2 diabetes is generally characterized by hyperglycemia, insulin resistance (reduced insulin sensitivity), and obesity, which is associated with not only diabetes but also hyperlipidemia and hypertension.Evidence from the past 10 years demonstrates that moderate intake of dark chocolate may exert protective effects against the development of type 2 diabetes risk factors; however, large-scale clinical trials are required.Several mechanisms have been proposed to explain the chocolate’s positive effects, not only on insulin sensitivity and vascular endothelial function but also its metabolic (fat and carbohydrate), antihypertensive, antithrombotic, and anti-inflammatory effects.Polyphenol-rich chocolate may potentially be used as a nutraceutical medication to help treat diabetes, strokes, and vascular dementia; thus, future studies should provide information on polyphenol content and the flavanol plasma levels achieved.
U2 - 10.1007/978-1-61779-803-0_25
DO - 10.1007/978-1-61779-803-0_25
M3 - Chapter
SN - 9781617798023
T3 - Nutrition and Health
SP - 341
EP - 353
BT - Chocolate in health and nutrition
A2 - Watson, Ronald R.
A2 - Preedy, Victor R.
A2 - Zibadi, Sherma
PB - Humana Press
CY - New York
ER -