PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans

Zack McDonald*, Kimberley Bennett, Anne Savage

*Corresponding author for this work

    Research output: Other contribution

    Abstract

    Review question
    What is the evidence that POPs alter the IGF1 signalling pathway?

    This may be broken down into;
    What is the evidence that POPs affect IGF1 functions, levels, transport or downstream effects? What specific POPs alter IGF1 function, IGF1 levels, IGF1 transport and IGF1 Receptor? What is the evidence for POP effect from different study designs in humans, animals, and in vitro studies?
    Original languageEnglish
    TypeProtocol registration
    Media of outputOnline - PROSPERO database produced by Centre for Reviews and Dissemination (CRD)
    PublisherCentre for Reviews and Dissemination (CRD) University of York
    VolumeCRD42023436855
    Publication statusPublished - 23 Jun 2023

    Publication series

    NamePROSPERO International prospective register of systematic reviews
    PublisherCentre for Reviews and Dissemination (CRD)

    Keywords

    • IGF1
    • Persistent organic pollutants
    • POPs
    • PCBs
    • Systematic review

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