PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans

Zack McDonald; Kimberley Bennett; Anne Savage

PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans

Zack McDonald^*
, Kimberley Bennett
, Anne Savage

^*Corresponding author for this work

Research output: Other contribution

Abstract

Review question
What is the evidence that POPs alter the IGF1 signalling pathway?

This may be broken down into;
What is the evidence that POPs affect IGF1 functions, levels, transport or downstream effects? What specific POPs alter IGF1 function, IGF1 levels, IGF1 transport and IGF1 Receptor? What is the evidence for POP effect from different study designs in humans, animals, and in vitro studies?

Original language	English
Type	Protocol registration
Media of output	Online - PROSPERO database produced by Centre for Reviews and Dissemination (CRD)
Publisher	Centre for Reviews and Dissemination (CRD) University of York
Volume	CRD42023436855
Publication status	Published - 23 Jun 2023

Publication series

Name	PROSPERO International prospective register of systematic reviews
Publisher	Centre for Reviews and Dissemination (CRD)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

IGF1
Persistent organic pollutants
POPs
PCBs
Systematic review

Access to Document

https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=436855

Investigating the effects of persistent organic pollutants (POPs) on insulin-like growth factor 1 (IGF-1) in grey seals
McDonald, Z. (Author), Bennett, K. (Supervisor) & Savage, A. (Supervisor), 18 Jun 2025
Student thesis: Masters Thesis › Masters by Research

File

Cite this

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title = "PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans",

abstract = "Review question What is the evidence that POPs alter the IGF1 signalling pathway? This may be broken down into; What is the evidence that POPs affect IGF1 functions, levels, transport or downstream effects? What specific POPs alter IGF1 function, IGF1 levels, IGF1 transport and IGF1 Receptor? What is the evidence for POP effect from different study designs in humans, animals, and in vitro studies?",

author = "Zack McDonald and Kimberley Bennett and Anne Savage",

year = "2023",

month = jun,

day = "23",

language = "English",

volume = "CRD42023436855",

series = "PROSPERO International prospective register of systematic reviews",

publisher = "Centre for Reviews and Dissemination (CRD) University of York",

type = "Other",

}

PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans. / McDonald, Zack; Bennett, Kimberley ; Savage, Anne.
Centre for Reviews and Dissemination (CRD) University of York. 2023, Protocol registration. (PROSPERO International prospective register of systematic reviews).

Research output: Other contribution

TY - GEN

T1 - PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans

AU - McDonald, Zack

AU - Bennett, Kimberley

AU - Savage, Anne

PY - 2023/6/23

Y1 - 2023/6/23

N2 - Review question What is the evidence that POPs alter the IGF1 signalling pathway? This may be broken down into; What is the evidence that POPs affect IGF1 functions, levels, transport or downstream effects? What specific POPs alter IGF1 function, IGF1 levels, IGF1 transport and IGF1 Receptor? What is the evidence for POP effect from different study designs in humans, animals, and in vitro studies?

AB - Review question What is the evidence that POPs alter the IGF1 signalling pathway? This may be broken down into; What is the evidence that POPs affect IGF1 functions, levels, transport or downstream effects? What specific POPs alter IGF1 function, IGF1 levels, IGF1 transport and IGF1 Receptor? What is the evidence for POP effect from different study designs in humans, animals, and in vitro studies?

M3 - Other contribution

VL - CRD42023436855

T3 - PROSPERO International prospective register of systematic reviews

PB - Centre for Reviews and Dissemination (CRD) University of York

ER -

PROSPERO: Systematic review on the effects of Persistent Organic Pollutants (POPs) on Insulin-like Growth Factors in both animals and humans

Abstract

Publication series

UN SDGs

Keywords

Access to Document

Fingerprint

Student theses

Investigating the effects of persistent organic pollutants (POPs) on insulin-like growth factor 1 (IGF-1) in grey seals

Cite this