Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 409-415 |
| Number of pages | 7 |
| Journal | Food Science and Nutrition |
| Volume | 1 |
| Issue number | 6 |
| Early online date | 5 Sep 2013 |
| DOIs | |
| Publication status | Published - Nov 2013 |
| Externally published | Yes |
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The bioaccessibility of eicosapentaenoic acid was higher from phospholipid food products than from mono‐ and triacylglycerol food products in a dynamic gastrointestinal model. / Domoto, Nobuhiko; Koenen, Marjorie E.; Havenaar, Robert; Mikajiri, Akihiro; Chu, Boon-Seang.
In: Food Science and Nutrition, Vol. 1, No. 6, 11.2013, p. 409-415.Research output: Contribution to journal › Article
TY - JOUR
T1 - The bioaccessibility of eicosapentaenoic acid was higher from phospholipid food products than from mono‐ and triacylglycerol food products in a dynamic gastrointestinal model
AU - Domoto, Nobuhiko
AU - Koenen, Marjorie E.
AU - Havenaar, Robert
AU - Mikajiri, Akihiro
AU - Chu, Boon-Seang
PY - 2013/11
Y1 - 2013/11
N2 - The bioaccessibility of eicosapentaenoic acid (EPA) in the forms of monoacylglycerol (EPA‐MAG), triacylglycerol (EPA‐TAG), and phospholipid (EPA‐PL) during gastrointestinal passage was compared in this study using a dynamic gastrointestinal model (TIM system). The TIM system simulated the average upper gastrointestinal tract conditions of healthy human adults after intake of a meal (fed state conditions). In this study, the three EPA‐rich oils were separately homogenized with full fat milk to obtain oil‐in‐water emulsions. Plain yogurt was added into the mixture at an emulsion/yogurt ratio of 4:1 (w/w) as the food matrix of the test products. The results show that the test meals containing EPA‐PL left the stomach compartment most efficiently in comparison with the gastric emptying of EPA‐MAG and EPA‐TAG. The PLs also showed a significantly (P < 0.05) higher bioaccessibility of EPA (75–80%) in comparison with MAG (30%) and TAG (38%). The better gastric emptying of EPA‐PL was likely related to the more stable emulsion of EPA‐PL in the test meal. EPA‐PL was delivered within the meal matrix into the duodenum instead of floating on the top of the test meal matrix. EPA‐MAG had the highest amount of EPA that did not leave the stomach (68% of the test meal). The results from this work indicate that EPA‐PL is a more effective form of EPA for a higher lipid bioaccessibility than MAG and TAG under the test conditions.
AB - The bioaccessibility of eicosapentaenoic acid (EPA) in the forms of monoacylglycerol (EPA‐MAG), triacylglycerol (EPA‐TAG), and phospholipid (EPA‐PL) during gastrointestinal passage was compared in this study using a dynamic gastrointestinal model (TIM system). The TIM system simulated the average upper gastrointestinal tract conditions of healthy human adults after intake of a meal (fed state conditions). In this study, the three EPA‐rich oils were separately homogenized with full fat milk to obtain oil‐in‐water emulsions. Plain yogurt was added into the mixture at an emulsion/yogurt ratio of 4:1 (w/w) as the food matrix of the test products. The results show that the test meals containing EPA‐PL left the stomach compartment most efficiently in comparison with the gastric emptying of EPA‐MAG and EPA‐TAG. The PLs also showed a significantly (P < 0.05) higher bioaccessibility of EPA (75–80%) in comparison with MAG (30%) and TAG (38%). The better gastric emptying of EPA‐PL was likely related to the more stable emulsion of EPA‐PL in the test meal. EPA‐PL was delivered within the meal matrix into the duodenum instead of floating on the top of the test meal matrix. EPA‐MAG had the highest amount of EPA that did not leave the stomach (68% of the test meal). The results from this work indicate that EPA‐PL is a more effective form of EPA for a higher lipid bioaccessibility than MAG and TAG under the test conditions.
U2 - 10.1002/fsn3.58
DO - 10.1002/fsn3.58
M3 - Article
VL - 1
SP - 409
EP - 415
JO - Food Science and Nutrition
JF - Food Science and Nutrition
SN - 2048-7177
IS - 6
ER -