@inproceedings{71cd71ac14bf4f88b2f43fe60b2efabb,
title = "The development of an amperometric biosensor based on the assembly of genetically engineered enzymes for the detection of explosives",
abstract = "A series of nitroreductases containing sequences of cysteine amino acids, enabling strong thiolate bonds to form on a gold electrode surface without the loss of enzyme activity, were genetically engineered. The cysteines enable the orientationally controlled immobilisation of the enzymes, removing the need for pre-treatment of the electrode surface with self-assembled monolayers or conducting polymers. The enzymatically modified electrodes were utilised in the development of an amperometric biosensor for the detection of explosives containing nitro-aromatic compounds. Preliminary results demonstrate detection levels down to 5 parts per trillion, signifying tremendous promise towards an in situ sensor for the detection of vapours from explosive compounds.",
author = "M. Kalaji and C. Gwenin and C. Kay",
year = "2009",
month = may,
day = "15",
doi = "10.1149/1.3118541",
language = "English",
isbn = "9781566777148",
series = "ECS Transactions",
publisher = "The Electrochemical Society",
number = "6",
pages = "93--102",
editor = "J. Li and R. Brown and H. Hatchet and P. Vanysek and C. Bruckner-Lea and M. Josowicz",
booktitle = "35 years of chemical sensors - an honorary symposium for Professor Jiri Janata's 70th birthday celebration",
address = "United States",
note = "35 Years of Chemical Sensors - An Honorary Symposium for Professor Jiri Janata's 70th Birthday Celebration - 215th ECS Meeting ; Conference date: 24-05-2009 Through 29-05-2009",
}