Although plasmids are ubiquitous amongst phytosphere pseudomonads, the advantage and costs of plasmids for the bacterial host remain unclear. The application of single-cell Raman spectral analysis to plasmid–bacterial systems under different environmental conditions offers a new means of determining the impact of plasmids on host cell physiology, metabolic status, and response to stress.
Ude, S., Bailey, M. J., Huang, W. E., & Spiers, A. J. (2007). The environmental plasmid pQBR103 alters the single-cell raman spectral profile of Pseudomonas fluorescens SBW25. Microbial Ecology, 53(3), 494-497. https://doi.org/10.1007/s00248-006-9191-0