The preparation of ketene dithioacetals and thiophenes from chloropyridines containing an active methylene group

Keith R. Sturrock; David H. Bremner; Grant Wishart

doi:10.3987/COM-10-S(E)59

The preparation of ketene dithioacetals and thiophenes from chloropyridines containing an active methylene group

Keith R. Sturrock, David H. Bremner, Grant Wishart

Abertay University

Research output: Contribution to journal › Special issue

2 Citations (Scopus)

163 Downloads (Pure)

Abstract

The base catalysed reaction of carbon disulphide with the active methylene groups of chloropyridines 4 and 7, followed by alkylation with reagents which also contain active methylene groups, lead to ketene dithioacetals. Further reaction with base afforded highly substituted thiophenes.

Original language	English
Pages (from-to)	1657 - 1662
Number of pages	6
Journal	Heterocycles
Volume	82
Issue number	2
DOIs	https://doi.org/10.3987/COM-10-S(E)59
Publication status	Published - Mar 2011

Fingerprint

Cite this

Sturrock, K. R., Bremner, D. H., & Wishart, G. (2011). The preparation of ketene dithioacetals and thiophenes from chloropyridines containing an active methylene group. Heterocycles, 82(2), 1657 - 1662. https://doi.org/10.3987/COM-10-S(E)59

@article{f89430f8c4ac4c9bb28a4c5e189f042d,

title = "The preparation of ketene dithioacetals and thiophenes from chloropyridines containing an active methylene group",

abstract = "The base catalysed reaction of carbon disulphide with the active methylene groups of chloropyridines 4 and 7, followed by alkylation with reagents which also contain active methylene groups, lead to ketene dithioacetals. Further reaction with base afforded highly substituted thiophenes.",

author = "Sturrock, {Keith R.} and Bremner, {David H.} and Grant Wishart",

year = "2011",

month = mar

doi = "10.3987/COM-10-S(E)59",

language = "English",

volume = "82",

pages = "1657 -- 1662",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "2",

}

TY - JOUR

T1 - The preparation of ketene dithioacetals and thiophenes from chloropyridines containing an active methylene group

AU - Sturrock, Keith R.

AU - Bremner, David H.

AU - Wishart, Grant

PY - 2011/3

Y1 - 2011/3

N2 - The base catalysed reaction of carbon disulphide with the active methylene groups of chloropyridines 4 and 7, followed by alkylation with reagents which also contain active methylene groups, lead to ketene dithioacetals. Further reaction with base afforded highly substituted thiophenes.

AB - The base catalysed reaction of carbon disulphide with the active methylene groups of chloropyridines 4 and 7, followed by alkylation with reagents which also contain active methylene groups, lead to ketene dithioacetals. Further reaction with base afforded highly substituted thiophenes.

U2 - 10.3987/COM-10-S(E)59

DO - 10.3987/COM-10-S(E)59

M3 - Special issue

VL - 82

SP - 1657

EP - 1662

JO - Heterocycles

JF - Heterocycles

SN - 0385-5414

IS - 2

ER -

Access to Document

10.3987/COM-10-S(E)59

BremnerHeterocyclesAuthor2011Accepted author manuscript, 46.8 KB