Abstract
| Original language | English |
|---|---|
| Title of host publication | Current developments in yeast research |
| Editors | Graham G. Stewart, Inge Russell |
| Publisher | PERGAMON-ELSEVIER SCIENCE LTD |
| Chapter | 87 |
| Pages | 561-567 |
| Number of pages | 7 |
| ISBN (Electronic) | 9780080253824 |
| ISBN (Print) | 9780080253657, 0080253652 |
| DOIs | |
| Publication status | Published - 1981 |
| Externally published | Yes |
| Event | Fifth International Yeast Symposium - London, Canada Duration: 20 Jul 1980 → 25 Jul 1980 |
Publication series
| Name | Advances in Biotechnology |
|---|---|
| Publisher | Pergamon |
| Volume | 4 |
Conference
| Conference | Fifth International Yeast Symposium |
|---|---|
| Country | Canada |
| City | London |
| Period | 20/07/80 → 25/07/80 |
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The regulation of cell division in yeast by magnesium. / Walker, Graeme M.; Duffus, John H.
Current developments in yeast research . ed. / Graham G. Stewart; Inge Russell. PERGAMON-ELSEVIER SCIENCE LTD, 1981. p. 561-567 (Advances in Biotechnology; Vol. 4).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - The regulation of cell division in yeast by magnesium
AU - Walker, Graeme M.
AU - Duffus, John H.
PY - 1981
Y1 - 1981
N2 - Cells of the fission yeast, Schizosaccharomyces pombe, and the budding yeast, Kluyveromyces fragilis, fail to divide in Mg-free minimal media but can be induced to divide synchronously on restoration of Mg to “exhausted” cultures. Mg-depleted S. pombe, cells appear abnormally long, lack cell plates and possess elongated nuclei. This, together with evidence of a late cell cycle arrest by the ionophore A23187, suggests that specific Mg limitation blocks cells late in the G2 phase of the cell cycle. Moreover, analysis of cell Mg in cultures synchronized by various techniques reveals that there is a fairly steady fall in Mg concentration as cells grow, terminating in a rapid influx of Mg just before division. These results lead to the hypothesis that intracellular Mg concentration is the transducer for size and consequently time, related control of the cell cycle.
AB - Cells of the fission yeast, Schizosaccharomyces pombe, and the budding yeast, Kluyveromyces fragilis, fail to divide in Mg-free minimal media but can be induced to divide synchronously on restoration of Mg to “exhausted” cultures. Mg-depleted S. pombe, cells appear abnormally long, lack cell plates and possess elongated nuclei. This, together with evidence of a late cell cycle arrest by the ionophore A23187, suggests that specific Mg limitation blocks cells late in the G2 phase of the cell cycle. Moreover, analysis of cell Mg in cultures synchronized by various techniques reveals that there is a fairly steady fall in Mg concentration as cells grow, terminating in a rapid influx of Mg just before division. These results lead to the hypothesis that intracellular Mg concentration is the transducer for size and consequently time, related control of the cell cycle.
U2 - 10.1016/C2013-0-03316-6
DO - 10.1016/C2013-0-03316-6
M3 - Conference contribution
SN - 9780080253657
SN - 0080253652
T3 - Advances in Biotechnology
SP - 561
EP - 567
BT - Current developments in yeast research
A2 - Stewart, Graham G.
A2 - Russell, Inge
PB - PERGAMON-ELSEVIER SCIENCE LTD
ER -