Triclosan – an update

S. Saleh, R. N. S. Haddadin, S. Baillie, Phillip J. Collier

    Research output: Contribution to journalArticlepeer-review

    42 Citations (Scopus)

    Abstract

    The discovery in 1998 that triclosan has a site-specific action in the bacterial cell as an inhibitor of NADH- or NADPH-dependent enoyl-acyl carrier protein reductase led to a lively debate in the scientific press. The thesis of this debate was that such a mode of action may allow triclosan to induce resistance and cross-resistance in bacterial cells. The debate last saw review in 2004, and this paper aims at updating our knowledge in this area, given recent research on the topic.
    Original languageEnglish
    Pages (from-to)87-95
    Number of pages9
    JournalLetters in Applied Microbiology
    Volume52
    Issue number2
    DOIs
    Publication statusPublished - Feb 2011

    Keywords

    • Antibiotics
    • Biocides
    • Mechanism of action
    • Resistance
    • Antimicrobials

    Fingerprint

    Dive into the research topics of 'Triclosan – an update'. Together they form a unique fingerprint.

    Cite this