Triclosan – an update

S. Saleh, R. N. S. Haddadin, S. Baillie, Phillip J. Collier

    Research output: Contribution to journalArticlepeer-review

    42 Citations (Scopus)


    The discovery in 1998 that triclosan has a site-specific action in the bacterial cell as an inhibitor of NADH- or NADPH-dependent enoyl-acyl carrier protein reductase led to a lively debate in the scientific press. The thesis of this debate was that such a mode of action may allow triclosan to induce resistance and cross-resistance in bacterial cells. The debate last saw review in 2004, and this paper aims at updating our knowledge in this area, given recent research on the topic.
    Original languageEnglish
    Pages (from-to)87-95
    Number of pages9
    JournalLetters in Applied Microbiology
    Issue number2
    Publication statusPublished - Feb 2011


    • Antibiotics
    • Biocides
    • Mechanism of action
    • Resistance
    • Antimicrobials


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