Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 87-95 |
| Number of pages | 9 |
| Journal | Letters in Applied Microbiology |
| Volume | 52 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2011 |
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Triclosan – an update. / Saleh, S.; Haddadin, R. N. S.; Baillie, S.; Collier, Phillip J.
In: Letters in Applied Microbiology, Vol. 52, No. 2, 02.2011, p. 87-95.Research output: Contribution to journal › Article
TY - JOUR
T1 - Triclosan – an update
AU - Saleh, S.
AU - Haddadin, R. N. S.
AU - Baillie, S.
AU - Collier, Phillip J.
PY - 2011/2
Y1 - 2011/2
N2 - The discovery in 1998 that triclosan has a site-specific action in the bacterial cell as an inhibitor of NADH- or NADPH-dependent enoyl-acyl carrier protein reductase led to a lively debate in the scientific press. The thesis of this debate was that such a mode of action may allow triclosan to induce resistance and cross-resistance in bacterial cells. The debate last saw review in 2004, and this paper aims at updating our knowledge in this area, given recent research on the topic.
AB - The discovery in 1998 that triclosan has a site-specific action in the bacterial cell as an inhibitor of NADH- or NADPH-dependent enoyl-acyl carrier protein reductase led to a lively debate in the scientific press. The thesis of this debate was that such a mode of action may allow triclosan to induce resistance and cross-resistance in bacterial cells. The debate last saw review in 2004, and this paper aims at updating our knowledge in this area, given recent research on the topic.
U2 - 10.1111/j.1472-765X.2010.02976.x
DO - 10.1111/j.1472-765X.2010.02976.x
M3 - Article
VL - 52
SP - 87
EP - 95
JO - Letters in Applied Microbiology
JF - Letters in Applied Microbiology
SN - 0266-8254
IS - 2
ER -