Triclosan – an update

S. Saleh, R. N. S. Haddadin, S. Baillie, Phillip J. Collier

Research output: Contribution to journalArticle

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Abstract

The discovery in 1998 that triclosan has a site-specific action in the bacterial cell as an inhibitor of NADH- or NADPH-dependent enoyl-acyl carrier protein reductase led to a lively debate in the scientific press. The thesis of this debate was that such a mode of action may allow triclosan to induce resistance and cross-resistance in bacterial cells. The debate last saw review in 2004, and this paper aims at updating our knowledge in this area, given recent research on the topic.
Original languageEnglish
Pages (from-to)87-95
Number of pages9
JournalLetters in Applied Microbiology
Volume52
Issue number2
DOIs
StatePublished - Feb 2011

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Saleh, S., Haddadin, R. N. S., Baillie, S., & Collier, P. J. (2011). Triclosan – an update. Letters in Applied Microbiology, 52(2), 87-95. DOI: 10.1111/j.1472-765X.2010.02976.x

Saleh, S.; Haddadin, R. N. S.; Baillie, S.; Collier, Phillip J. / Triclosan – an update.

In: Letters in Applied Microbiology, Vol. 52, No. 2, 02.2011, p. 87-95.

Research output: Contribution to journalArticle

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Saleh, S, Haddadin, RNS, Baillie, S & Collier, PJ 2011, 'Triclosan – an update' Letters in Applied Microbiology, vol 52, no. 2, pp. 87-95. DOI: 10.1111/j.1472-765X.2010.02976.x

Triclosan – an update. / Saleh, S.; Haddadin, R. N. S.; Baillie, S.; Collier, Phillip J.

In: Letters in Applied Microbiology, Vol. 52, No. 2, 02.2011, p. 87-95.

Research output: Contribution to journalArticle

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Saleh S, Haddadin RNS, Baillie S, Collier PJ. Triclosan – an update. Letters in Applied Microbiology. 2011 Feb;52(2):87-95. Available from, DOI: 10.1111/j.1472-765X.2010.02976.x